Rhodiola Rosea is a plant native to the arctic regions of Europe, Asia, and North America. It has been used for centuries in traditional medicine in Russia and Scandinavian countries. Known for its adaptogenic properties, Rhodiola is used to enhance physical endurance and mental performance, and to help manage stress ^[1].

Rhodiola Rosea functions primarily by interacting with various physiological systems, including the HPA axis (hypothalamic-pituitary-adrenal axis), which plays a significant role in the body's stress response. Its active components, salidroside and rosavins, are thought to be responsible for its stress-reducing effects ^[2].

Rhodiola Rosea is associated with several health benefits, supported by scientific research. These include:

- Enhanced Mental Performance: Rhodiola Rosea has been shown to improve cognitive functioning in persons experiencing burnout, leading to improvements in associated symptoms like fatigue and poor concentration ^[3].

- Stress Reduction: Rhodiola's adaptogenic properties help the body adapt to stress by balancing the body's physiological response, reducing the symptoms of stress and burnout ^[4].

- Physical Performance: It can enhance physical performance and reduce exercise-induced fatigue, as seen in various human trials ^[5].

Rhodiola Rosea is generally safe and well-tolerated, but some individuals might experience side effects such as dry mouth, restlessness, insomnia, and increased blood pressure ^[6]. It is always best to consult with a healthcare professional before beginning any new supplement regimen.

Rhodiola Rosea might interact with certain medications, such as antidepressants, anticoagulants, and anti-diabetic drugs. Always consult a healthcare professional before starting Rhodiola if you are taking any medications ^[7].

Rhodiola Rosea dosage can vary widely depending on the specific extract and the purpose for which it's being used. However, a common dosage range is between 200 to 600 mg per day of an extract standardized to contain 2-3% rosavins and 0.8-1% salidroside, two of the most important active compounds in Rhodiola Rosea ^[8].

Some studies have used doses up to 680 mg to 1700 mg daily, divided into two doses ^[9]. However, it is always advised to start with a lower dose to assess tolerance, then gradually increase as needed.

It's typically recommended to take Rhodiola Rosea on an empty stomach, but not before bed, due to its stimulating effects. As with any supplement, it's essential to consult with a healthcare professional before starting a new regimen.